TABLE 3.
XTT-based pharmacodynamic analysis of PNT activities against two Fusarium spp. and two developmental programs in two culture mediaa
| Medium | Species | Developmental program | PNT conc (μg/ml)
|
|
|---|---|---|---|---|
| EC50 | EC90 | |||
| RPMI-2 | F. solani | Conidial | 3.9 | 29.7 |
| Hyphal | 53.1 | >128 | ||
| F. oxysporum | Conidial | 1.6 | 5.8 | |
| Hyphal | 30.3 | >128 | ||
| YNB | F. solani | Conidial | 1.4 | 8.6 |
| Hyphal | 50.5 | >128 | ||
| F. oxysporum | Conidial | 0.5 | 1.57 | |
| Hyphal | 17.8 | >128 | ||
a
The pharmacodynamic analysis of PNT against conidia was based on three isolates each of F. solani and F. oxysporum, whereas that of PNT against hyphae was based on two isolates each of F. solani and F. oxysporum.