TABLE 5.
Results of repeat and/or follow-up tympanocenteses among patients classified as clinical failures at day 28 to 32 (microbiologically evaluable intent-to-treat population)
Treatment group | Patient | Baseline pathogen | Pathogen recovered at follow-up | Comments |
---|---|---|---|---|
Azithromycin | I | S. pneumoniae | No growth | |
J | H. influenzae | H. influenzae | Azithromycin MIC at baseline and follow-up, 1 and 2 μg/ml, respectively. Both isolates were β-lactamase positive | |
K | S. pneumoniae | S. pneumoniae | Azithromycin MIC at baseline and follow-up, 0.12 and 8 μg/ml, respectively | |
L | H. influenzae | M. catarrhalis | ||
Amoxicillin-clavulanate | M | H. influenzae | No growth | |
N | H. influenzae | H. influenzae | Amoxicillin MIC at both baseline and follow-up, 0.5 μg/ml. Both isolates were β-lactamase negative | |
O | S. pneumoniae | H. influenzae |