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. 2003 Oct;47(10):3318–3320. doi: 10.1128/AAC.47.10.3318-3320.2003

FIG. 1.

FIG. 1.

Southern hybridization of EcoRV-digested genomic DNA from E. faecalis with a 23S rRNA probe. The position of the 23S rRNA gene copy that acquires the mutation is indicated by the arrow with the asterisk to the left of the gel. The positions of the two bands resulting from EcoRV digestion of the 23S rRNA gene that acquires the G2505A mutation in the two resistant UV202 mutants are indicated by the arrows to the right of the gel. Lane 1, E. faecalis UV202; lane 2, linezolid-resistant UV202 mutant (MIC of 2 μg/ml); lane 3, linezolid-resistant UV202 mutant (MIC of 16 μg/ml).