TABLE 3.
MICs for H. influenzae
| Drug | MIC (μg/ml)
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| β-Lactamase-negative strains (n = 50)
|
β-Lactamase-positive strains (n = 79)
|
BLNAR strains (n = 21)
|
All strains (n = 150)
|
|||||||||
| Range | 50% | 90% | Range | 50% | 90% | Range | 50% | 90% | Range | 50% | 90% | |
| XRP 2868 | ≤0.06-1.0 | 0.25 | 0.5 | ≤0.06-1.0 | 0.25 | 1.0 | ≤0.06-1.0 | 0.25 | 0.5 | ≤0.06-1.0 | 0.25 | 1.0 |
| RPR 132522 | 0.12-1.0 | 0.25 | 0.5 | 0.12-1.0 | 0.25 | 0.5 | 0.12->8.0 | 0.25 | 0.5 | 0.12->8.0 | 0.25 | 0.5 |
| RPR 202868 | 2.0->64 | >64 | >64 | 2.0->64 | >64 | >64 | 2.0->64 | >64 | >64 | 2.0->64 | >64 | >64 |
| Pristinamycin | 0.5-2.0 | 1.0 | 2.0 | 0.12-4.0 | 1.0 | 2.0 | 0.25-4.0 | 1.0 | 1.0 | 0.12-4.0 | 1.0 | 2.0 |
| Quinupristin/dalfopristin | 1.0-8.0 | 2.0 | 4.0 | 0.25-8.0 | 4.0 | 4.0 | 1.0-8.0 | 2.0 | 4.0 | 0.25-8.0 | 2.0 | 4.0 |
| Quinupristin | 16->64 | 32 | >64 | 8.0->64 | 32 | >64 | 16->64 | 64 | >64 | 8.0->64 | 32 | >64 |
| Dalfopristin | 1.0-8.0 | 2.0 | 8.0 | 1.0-32 | 4.0 | 8.0 | 1.0->64 | 2.0 | 4.0 | 1.0->64 | 2.0 | 8.0 |
| Erythromycin | 2.0-16 | 4.0 | 8.0 | 0.5-16 | 4.0 | 8.0 | 1.0-16 | 4.0 | 8.0 | 0.5-16 | 4.0 | 8.0 |
| Azithromycin | 0.5-2.0 | 1.0 | 2.0 | 0.12-2.0 | 1.0 | 2.0 | 0.5-8.0 | 1.0 | 2.0 | ≤0.12-8.0 | 1.0 | 2.0 |
| Clarithromycin | 4.0-32 | 8.0 | 16 | 1.0-64 | 8.0 | 8.0 | 4.0-16 | 4.0 | 16 | 1.0-64 | 8.0 | 16.0 |