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Amino acid polymorphisms in different Vα13 sequences from the NOD/bdc, BALB/c ByJ, and C57BL/6J mice
| Vα | Strain | aa15 | aa23 | aa26 | aa60 | aa62 |
|---|---|---|---|---|---|---|
| 13.3 | NOD | G | S | D | T | G |
| 13.1 | NOD, BALB/c, C57BL/6 | G | T | N | T | G |
| 13.2a | BALB/c | R | T | N | I | G |
| 13.2b | C57BL/6 | G | T | N | I | E |
| 13.4 | C57BL/6 | G | S | D | I | E |
Amino acid positions 23 and 26 are within the CDR1 region, whereas positions 60 and 62 are near CDR2. Homology to Vα13.3 is indicated by boldface type. The amino acid sequences are identical at the other positions not listed.
