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Response of spleen leukocytes from PNP-deficient mice to con A and IL-2. Spleen leukocytes were stimulated alone or in combination with con A (0.5 μg/ml) and/or IL-2 (6.5 or 60 units/ml). Results are the mean ± SD for the following numbers of animals: C57BL/6J, 7; B6-NPE, 3; B6-NPF, 6; B6-NPG, 4. Letters indicate significant differences (P = 0.05) among strains for each set of conditions.
