Table 2.
Phenotype and number of thymocytes in PNP-deficient mice
| Surface Antigen | C57BL/6J (n = 10) | B6-NPE (n = 4) | B6-NPF (n = 4) | B6-NPG (n = 3) |
|---|---|---|---|---|
| Thy-1+ | 99.8 ± 0.3a | 99.8 ± 0.4a | 98.7 ± 1.4a | 93.7 ± 4.2b |
| CD4−CD8− | 2.9 ± 0.6a | 3.9 ± 2.3a | 8.7 ± 3.6a | 24.0 ± 9.8b |
| CD4+CD8+ | 88.0 ± 2.8a | 86.1 ± 4.0ab | 75.9 ± 7.7b | 42.6 ± 18.4c |
| CD4+CD8− | 6.3 ± 1.9a | 7.0 ± 2.9a | 9.0 ± 1.4a | 23.6 ± 9.2b |
| CD4−CD8+ | 2.8 ± 1.0a | 3.0 ± 1.1a | 6.3 ± 3.0b | 9.8 ± 1.4c |
Results are the mean ± SD for the number of mice given in parenthesis between 8 and 10 months of age. Multiple comparisons among means were made using the Student–Newmann–Keuls test (P = 0.05).
Letters indicate significant differences (P = 0.05) among strains for each surface antigen subtype.