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Effect of administration of c-PTIO on EAE in SWXJ-14 mice. Four days after immunization with PLP, SWXJ-14 mice were either left untreated (♦) or treated (▪) either once (A) or twice (B) daily with 2 mg c-PTIO. In both cases, treatment was continued until day 16 after immunization (arrows). Severity scores were graded and are expressed as a mean.
