TABLE 4.
Comparison of GDP-mannose pyrophosphorylases and phosphomannomutases from serogroups B, C1, C2, and O:6,14
| Gene | Protein size (amino acids) | % G+C content | % Amino acid identity |
|---|---|---|---|
| GDP-mannose pyrophosphorylases | |||
| manC (H) | 472 | 36.4 | |
| manC (C1) | 472 | 39.0 | 58.5 |
| manC (C2) | 474 | 39.0 | 56.4 |
| manC (B) | 480 | 40.3 | 57.0 |
| cpsBa (B) | 481 | 60.4 | 59.1 |
| Phosphomannomutases | |||
| manB (O:6,14) | 476 | 37.4 | |
| manB (C1) | 457 | 61.3 | 14.9 |
| manB (C2) | 479 | 37.6 | 58.2 |
| manB (B) | 478 | 40.9 | 57.4 |
| cpsGa (B) | 457 | 61.7 | 14.9 |
a
cpsB and cpsG are isogenes of manC and manB, respectively, from S. enterica serotype Typhimurium LT2, encoding enzymes that synthesize GDP-mannose (37).