Table 1.

Transgene expression and leukemia incidence

Line	PmlRarα expression*	APL cases	Age at diagnosis, days	Mice reaching age 174 days†
506	++	2	174, 195	45
553	+	3	78, 174, 265	79
556	+++	5	92, 143, 149, 176, 203	16
565	++	0		31
569	+	1	155	12
608	+	1	247	34

^*Relative levels based on visual comparison of western blot and immunofluorescence. 

^†Includes living mice and those aged at least 174 days at death (median age at diagnosis of APL).