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Inhibition of [3H]NPA binding by GTPγS in CHO cell membranes expressing the dopamine D2 receptor. [3H]NPA binding was carried out as described in the Materials and methods section. Data are expressed as a percentage of total high-affinity [3H]NPA binding defined as that inhibited by high concentrations of nucleotide. Data are from a single representative experiment, which was carried out three times with similar results.
