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A curiosity-driven experiment leads to the discovery of the genes required for NMD in yeast
| Growth without histidine
|
||
|---|---|---|
| Genotype | 30° | 37° |
| Wild type | + | + |
| his4-38 suf1wt UPF1wt | − | − |
| his4-38 SUFIfs UPF1wt | + | − |
| his4-38 SUF1fs upf1Δ | + | + |
| his4-38 suf1wt upf1Δ | − | − |
The phenotypes of allosuppressors that were shown to be mutations in the yeast UPF genes are shown.
