TABLE 2.

Average frequencies of the derived nucleotide in various subsets of SNPs in regions aligned to the Neanderthal and chimpanzee sequences

	HapMap sample
	European	Han Chinese	Japanese	Yoruban
N-derived	0.654	0.660	0.659	0.582
N-derived (CpG)	0.692	0.772	0.766	0.606
N-ancestral	0.267	0.279	0.278	0.282
N-ancestral (CpG)	0.281	0.326	0.331	0.282

N-derived are sites at which the Neanderthal has a different nucleotide than in the chimpanzee sequence (n = 177); N-derived (CpG) are N-derived sites at which the human SNP is in a CpG pair (n = 24); N-ancestral are sites at which the Neanderthal and chimpanzee have the same nucleotide (n = 461); N-ancestral (CpG) are the N-ancestral sites at which the human SNP is in a CpG pair (n = 84).