TABLE 4.

HapMap SNPs in exons for which the Neanderthal nucleotide could be determined

Name	Chr	Syn/Non	Nean	Chim	Hum	Ceu	Hcb	Jpt	Yri
N-derived
rs157397	17	Syn	C	T	C/T	0.95	0.56	0.7	0.77
N-ancestral
rs11208299	1	Non	T	T	G/T	0.708	0.567	0.409	0.30
rs8192506	2	Non	A	A	G/A	0.05	0	0	0
rs449643	6	Non	G	G	A/G	0.092	0.024	0.058	0.24
rs2304824	15	Non	G	G	A/G	0.525	0.722	0.716	0.18
rs17009819	4	Syn	C	C	T/C	0	0	0	0.12

Name, SNP identifier used by build 36.1 of the HapMap database; Chr, number of human chromosome; Syn, synonymous change; Non, nonsynonymous change; Nean, nucleotide of the Neanderthal; Chim, nucleotide of build 2, version 1 of the chimpanzee reference sequence (pantro2); Hum, pair of nucleotides polymorphic in the HapMap database; Ceu, frequency of the derived nucleotide in the European HapMap database; Hcb, frequency of the derived nucleotide in the Han Chinese HapMap database; Jpt, frequency of the derived nucleotide in the Japanese HapMap database; Yri, frequency of the derived nucleotide in the Yoruban HapMap database. The nucleotide in the chimpanzee sequence is assumed to be ancestral.