TABLE 2.
Down-regulation in expression of individual genes in detrusor myocytes/bladder wall and corporal myocytes
Affymetrix probesets | Fold change | Gene name (DOWN) | Gene symbol |
---|---|---|---|
Detrusor myocytes | |||
X86789_at | 96 | Synuclein-γ | Sncg |
J05592_g_at | 62 | Protein phosphatase 1, regulatory (inhibitor) subunit 1A | Ppp1r1a |
X65036_at | 62 | Integrin-α7 | Itga7 |
rc_AA925248_at | 25.3 | Na+ channel, voltage-gated, type 6, α polypeptide | Scn6a |
AF031880_AT | 20 | Neurofilament, light polypeptide | Nfl |
D45920_at | 9.7 | 130 kDa-Ins(1,4,5)P3 binding protein | LOC84587 |
rc_AA892251_at | 9.6 | Arginine vasopressin receptor 1A | Avpr1a |
L03382_at | 9.4 | Phospholamban | Plm |
X04139_s_at | 9.4 | Protein kinase C, β1 | Prkcb1 |
M31838_at | 8.5 | Tachykinin receptor 2 | Tacr2 |
U50185_AT | 7.8 | Myosin phosphatase, target subunit 1 | Mypt1 |
rc_AI230211_s_at | 7.2 | K+ voltage gated channel, Shal-related family, member 3 | Kcnd3 |
AA799276_AT | 6.6 | ATPase, Ca2+ transporting, cardiac muscle, slow twitch 2 | Atp2a2 |
D85435_at | 6.4 | Protein kinase C, δ binding protein | Prkcdbp |
M17526_G_AT | 6.2 | Guanine nucleotide binding protein, α o | Gnao |
U21101_at | 4.7 | cGMP-stimulated phosphodiesterase | Pde2a |
M34643_AT | 3.5 | Neurotrophin-3 (HDNF/NT-3) | Ntf3 |
Z12152_AT | 3.2 | Neurofilament 3, medium | Nef3 |
RC_AI145367_AT | 1.7 | Adenylyl cyclase-associated protein 2 | Cap2 |
U17971_AT | 1.5 | Protein tyrosine phosphatase 2E | Ptp2E |
M16407_AT | 1.4 | Cholinergic receptor, muscarinic 3 | Chrm3 |
Corporal myocytes | |||
rc_AI231472_s_at | 380 | Collagen, type 1, α1 | Col1a1 |
rc_AA900769_s_at | 70.8 | Smooth muscle α-actin | Acta2 |
Z78279_g_at | 36 | Collagen, type 1, α1 | Col1a1 |
Z78279_at | 18.2 | Collagen, type 1, α1 | Col1a1 |
rc_AA944422_at | 14.6 | Calponin 3, acidic | Cnn3 |
X70369_s_at | 10.8 | Collagen, type III, α1 | Col3a1 |
rc_AI176170_at | 6.9 | FK506-binding protein 1a | Fkbp1a |
rc_AI228738_s_at | 5.7 | FK506-binding protein 1a | Fkbp1a |