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Kidney disposition and stability of oligos 1 and 14–16. A plot of kidney concentration versus the time course of oligo-derived radioactivity (35S) is shown at the left. The kidney samples were extracted, and the oligos were analyzed by gel electrophoresis and autoradiographed. (A) Oligo 14. (B) Oligo 15. (C) Oligo 16. (The data for oligo 1 are derived from a previous study, ref. 16.)
