PE-induced vasoconstriction in the dorsal artery in the absence or presence of 1, 10 or 100 nM prazosin (non-selective antagonist, n=7), RS 100329 (α1A-AR antagonist, n=6), Rec 15/2615 (α1B-AR antagonist, n=4) or BMY 7378 (α1D-AR antagonist, n=6). A rightward shift of the PE CRC was observed at 1 and 10 nM RS 100329, but no further rightward shift occurred at 100 nM. All PE response data were taken from second CRCs in the absence or presence of antagonist.