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UK 14 304-induced (0.1–30 nM) vasoconstriction in the dorsal artery followed by addition of 1–1000 nM rauwolscine (rauw, non-selective α2-AR, n=5), prazosin (praz, non-selective α1-AR, n=5) or BRL 44408 (BRL, α2A-AR selective, n=6) compared to a decrease in tone with the time control (time, n=4).
