Figure 3.

(a) Rimonabant administration (0.03, 0.1, 1, 3 mg kg⁻¹ i.p.) before the active avoidance test showed no effect in wild-type mice. Data are expressed as a ratio between conditioned changes and total changes and represent mean±s.em. n=16–19 mice per experimental group. (b) Nicotine administration (0.5 mg kg⁻¹ s.c.) before the active avoidance test produced no effect in wild-type mice. There was no effect when animals were pretreated with rimonabant (0.03, 0.1, 1, 3 mg kg⁻¹ i.p.) either. Data are expressed as a ratio between conditioned changes and total changes. Data represent mean±s.e.m. n=16–19 mice per experimental group.