Recognition index measured at 24 h after the first trial, was increased in wild-type mice treated with nicotine (0.5 mg kg−1 s.c.), whereas animals that received rimonabant (0.03, 0.1, 1, 3 mg kg−1 i.p.) or both, rimonabant (0.03, 0.1, 1, 3 mg kg−1 i.p.) and nicotine (0.5 mg kg−1 s.c), exhibited a similar recognition index. Data represent mean±s.e.m. n=8–14 mice per experimental group.