Table 2.

Effects of saline, atenolol and ivabradine on myocardial wall thickening at rest and during exercise

	Baseline	Rest	Paced rest	Exercise	Exercise paced
EDWT (mm)
Saline	8.9±0.5	8.8±0.5	9.0±0.6	8.7±0.5	9.0±0.6
Atenolol	8.9±0.6	8.6±0.5	8.7±0.5	8.3±0.5*	9.3±0.6
Ivabradine	8.8±0.5	8.7±0.6	8.9±0.6	8.5±0.5	9.2±0.6
SWT (mm)
Saline	2.6±0.2	2.6±0.2	2.5±0.2	3.7±0.5	3.4±0.6
Atenolol	2.6±0.1	2.4±0.3	2.2±0.2	3.4±0.4	2.3±0.2
Ivabradine	2.6±0.2	2.6±0.2	2.3±0.2	4.4±0.5*	3.5±0.6
PSWT (mm)
Saline	0.25±0.02	0.21±0.03	0.21±0.04	0.15±0.04	0.16±0.05
Atenolol	0.23±0.04	0.35±0.07*	0.38±0.07*	0.30±0.04*	0.37±0.07*
Ivabradine	0.24±0.06	0.22±0.07	0.22±0.03	0.11±0.04	0.17±0.05

Abbreviations: EDWT, end-diastolic wall thickness; PSWT, postsystolic wall thickening; SWT, systolic wall thickening.

Values are mean±s.e.m., n=6 dogs in all sequences. Doses for atenolol and ivabradine were 1 mg kg⁻¹.

^*P<0.05 vs saline.