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Effect of budesonide on MDR1 mRNA expression in LS180 (a) and Caco-2 (b) cell lines. Cells were incubated for 48 h and mRNA expression was determined by quantitative real-time PCR. Rifampicin was used as a positive control for MDR1 induction in LS180 cells. Results are normalized to control cells and expressed as mean±s.e.m. (n=4). *P<0.05, ***P<0.001 vs control cells.
