Table 2.

Comparison of characteristics of [³⁵S]TBPS binding in rat and human postmortem cortex and cerebellum membranes

Brain region	KD (nM)	Bmax (pmol mg protein−1)
Human cortex	37±1.3*	0.79±0.13*
Human cerebellum	36±4.9*	0.74±0.09*
Rat cortex	19±1	1.56±0.09
Rat cerebellum	18±2	1.25±0.12

Abbreviation: [³⁵S]TBPS, [³⁵S]t-butylbicyclophosphorothionate.

Data shown are mean±s.e.m. (n=3–4).

^*P<0.05; comparison with corresponding rat tissue using an unpaired t-tests.