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NO production by methylamine is reduced by L-NAME pre-treatment. Twelve-hours-starved mice were pretreated i.c.v. with L-NAME and then injected with methylamine (MET, 15 μg). Perfusates collected after 120 min were analyzed for NO content. Results are expressed as NO release (% over basal) at 120 min. *P<0.05 vs basal; n=4.
