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. 2007 Apr 16;151(4):467–475. doi: 10.1038/sj.bjp.0707249

Figure 5.

Figure 5

Inhibition of contractility of pig bladder smooth muscle. (a) A-251179 suppressed carbachol (0.3 μM)-induced bladder smooth muscle contraction in a glyburide-sensitive manner. Note the intrinsic spontaneous activity of smooth muscle was reduced in the presence of A-251179. (b) Concentration-dependent inhibition curves demonstrating suppression of spontaneous contractions (solid circles) and that evoked by carbachol (solid squares) and low-frequency field stimulation (solid triangles).