Effects of A-251179 on urodynamic parameters of the neurogenic hyperactivity model. The figure shows changes in bladder capacity (a), threshold pressure (b), voiding efficiency (c), time between voids (d) and mean arterial pressure (e) evoked at various concentrations of A-251179. Values shown are means±s.e.m. of six separate determinations (*P<0.05, **P<0.01, paired t-test).