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. 2007 Apr 2;151(4):541–550. doi: 10.1038/sj.bjp.0707242

Figure 1.

Figure 1

Concentration–response curves for the inhibitory effects of L-arginine (0.01–4.7 mM), L-citrulline (0.01–4.7 mM) and SIN-1 (1–100 μM) on [3H]ACh release from motor nerve terminals stimulated with 5 Hz-trains (750 pulses). Abscissa, log of the concentration (M) of L-arginine (0.01–4.7 mM, squares), L-citrulline (0.01–4.7 mM, circles) and SIN-1 (1–100 μM, triangles), applied 15 min before S2. Ordinate, percentage change in S2/S1 ratio as compared with the S2/S1 ratio in control experiments. Zero per cent represents identity between the two ratios, negative values indicate inhibition of evoked [3H]ACh release. Each point represents the mean±s.e.m. of 4–11 experiments.