Table 1.
Effects of fructose and aminoguanidine on body weight, LV weight, glucose level and basic hemodynamic data in male Wistar rats
| Variable | NC (n=10) | NC+AG (n=10) | FF (n=10) | FF+AG (n=10) |
|---|---|---|---|---|
| BW (g) | 325.3±9.2 | 320.0±5.1 | 312.6±6.0 | 315.7±6.4 |
| LVW (g) | 0.618±0.012 | 0.612±0.019 | 0.593±0.015 | 0.615±0.013 |
| LVW/BW | 0.189±0.003 | 0.191±0.004 | 0.190±0.002 | 0.195±0.003 |
| Glucose (mM) | 5.69±0.17 | 6.16±0.19 | 5.90±0.16 | 6.07±0.27 |
| HR (beat min−1) | 452.5±14.5 | 460.2±14.7 | 447.9±8.7 | 453.2±9.6 |
| CO (ml s−1) | 2.06±0.11 | 2.02±0.16 | 1.75±0.07* | 2.18±0.10† |
Abbreviations: AG, aminoguanidine; BW, body weight; CO, cardiac output; FF, fructose-feeding group; HR, basal heart rate; LVW, left ventricular weight; NC, normal controls.
Notes: All values are expressed as means±s.e.m.
*
Statistical difference (P<0.05) from the NC.
†
Statistical difference (P<0.05) from the FF.