Table 1.
Contractile response to KCl and to phenylephrine of the aortic rings with (+) or without (−) perivascular adipose tissue (PVAT) or endothelium (E) from male Wistar rats (300–350 g)
|
KCl |
Phenylephrine |
|||
|---|---|---|---|---|
| (60 mM; g) | Emax (% of KCl) | EC50 (μM) | n | |
| PVAT+E+ | 1.8±0.1 | 101±3a | 0.28±0.05a | 7 |
| PVAT-E+ | 1.7±0.07 | 124±2b,a | 0.11±0.01b,c | 7 |
| PVAT+E- | 1.9±0.19 | 132±2b,a | 0.14±0.03 | 6 |
| PVAT-E- | 1.5±0.05 | 161±3b | 0.06±0.01b | 6 |
No statistical difference was found between PVAT+ E− and PVAT− E+ rings (P>0.05).
P<0.01 versus PVAT− E− rings.
P<0.01 versus PVAT+ E+ rings.
P<0.05 versus PVAT− E− rings.