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. 2007 May 14;151(5):688–700. doi: 10.1038/sj.bjp.0707273

Table 1.

Summary of experimental results of HU210 on DMTP and reference memory and retention in the water maze, as well as electrophysiological responses of single hippocampal neurons

  DMTP
 Reference memory
 Retention Electrophysiology
  30 s 1 h Trial 1 Trial 4    
Path length NS NS ↑ *
No reversal		 ↑ *
No reversal		 *
Impairment		 Frequency
Latency to target area NS NS ↑ *
No reversal		 ↑ *
Reversal with AM281 1.5 mg kg−1 		No reversal with AM281 or SR ↑ * of bursts
Swim speed ↑ * ↑ * ↑ *
No reversal		 NS   ↑ * of spikes
Thigmotaxis NS NS ↑ *
No reversal		 HU210+AM281 or SR impaired   No reversal with AM281

Abbreviations: DMTP, delayed-matching-to-position; NS, not significant.

Arrows indicate an increase or decrease in respective measures, together with asterisks denoting their significance P<0.05.