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. 2007 May 29;151(6):844–850. doi: 10.1038/sj.bjp.0707302

Figure 6.

Figure 6

Involvement of PPAR activation in the anti-inflammatory effect of phosphatidylserine liposomes. (a) Effects of PPAR antagonists on PS anti-inflammatory effects. The PPAR-γ non-selective antagonist, BADGE (100 mg kg−1, intraperitonealy) was injected 2 h before PS (100 mg kg−1, intraperitonealy) and the selective antagonist GW9662 (30 nmol per paw) was injected 30 min before PS. (b) Effects of PPAR antagonists on rosiglitazone (Rosi; 30 mg kg−1, intraperitonealy) anti-inflammatory effects. *P<0.05 compared to carrageenan (Carr); #P<0.05 compared to carrageenan+PS or + rosiglitazone animals. Statistical analysis was performed using ANOVA test followed by Bonferroni's post hoc t-test. ANOVA, analysis of variance; PPAR, peroxisome proliferator-activated receptors; PS, phosphatidylserine.