Orthogonal regression (solid line; line of identity dotted line) between AUC values obtained from the integrated p.o. (2x)/i.v. pharmacokinetic modelling and those from the noncompartmental analysis following i.v. (3 mg as an infusion over 40 min, a, ○, n=12) and single p.o. (12 mg, b, ▪, n=2×12) administrations of HTF.