Figure 6.
Effect of delphinidin on the PDGFAB-induced phosphorylation of ERK1/2, p38 MAPK and JNK in VSMCs. VSMCs were exposed to either solvent (0.1% DMSO) or delphinidin (30 μM) for 30 min before the addition of PDGFAB for the indicated time. Thereafter, the phosphorylation level of p38 MAPK, JNK and ERK1/2 was assessed by Western blot analysis. Total amount of p38 MAPK is also shown. A representative Western blot is shown in (a). The corresponding cumulative data for p38 MAPK phosphorylation (zero time levels=100) is shown in (b) and the corresponding cumulative data for JNK phosphorylation is shown in (c). *Significantly different from corresponding values without delphinidin; n=3; P<0.05.