Table 2.
Putative and established metabolic ratios of various CYP marker reactions in 30 healthy young male volunteers, with and without concomitant administration of diclofenac (Dic, n=6), disulfiram (Dis, n=6), itraconazole (Itra, n=6), erthyromycin (Ery, n=6) and grapefruit juice (Gra, n=6). For each interaction, the Hodges-Lehmann point estimates of the median differences with the exact 95% confidence intervals are provided.