Table 8.

A meta-analysis of 26 trials involving the use of heparin anticoagulation after acute myocardial infarction. Events refer to those occurring before hospital discharge. Most of the patients (62,067) in the aspirin plus heparin vs aspirin alone group come from GISSI-2 [31] and ISIS-3 [30] where the regimen was 12,500 units subcutaneously twice daily. Data has been derived from Collins et al. [34]. Values are mean±s.d. The trials that did not use aspirin used thrombolysis in 14% patients while those using aspirin used thrombolysis in 93% cases.