Plasma concentrations of uric acid (▿, ▾), hypoxanthine (◊, ♦), xanthine (□, ▪), and the sum of uric acid, hypoxanthine, and xanthine ((), ()), after oral administration of 200 mg allopurinol to elderly (solid symbols) and young subjects (open symbols). Note that the scale for hypoxanthine and xanthine (right y-axis) is 10-fold expanded compared with that for uric acid. Values are means±s.e. mean.