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. 2000 Aug;50(2):116–124. doi: 10.1046/j.1365-2125.2000.00218.x

Table 2.

Population pharmacokinetic parameters for BUD after repeated dose administration from a pMDI in seven men using mixed effects model.

Parameter Estimate Standard error
k12 (h−1) 3.82 0.598
V/F (l) 498 62.4
k20 (h−1) 0.284 0.0134
ω11* 1.34 0.833
ω22* 0.076 0.0465
ω33*
σ11 0.148 0.0152
*

The variances of η (Equation 8) refer to the random effects on k12 (absorption rate constant), V/F, and k20 (elimination rate constant), respectively. ω33 could not be estimated with confidence.