Table 2.
Data relative to the cases of drug-induced liver injury including suspected drugs, types of liver injury, clinical symptoms, criteria of serioussness, labellings in French SPC and causality scores.
| Drugs | Liver injury | Clinical symptoms | Seriousness | Labelling SPC | Causality score |
|---|---|---|---|---|---|
| Amineptine | Cholestatic | Abdominal pains + hepato-cellular failure | Life threathening | Labelled | Possible |
| Chlorpromazine + Haloperidol + clomipramine | Mixed | Abdominal pains | Hospitalization | Labelled | Possible |
| Clonazepam | Mixed | No | Prolongation of hospitalization | Unlabelled | Possible |
| Fenofibrate | Cholestatic | No | Non serious | Labelled | Possible |
| Fluindione | Mixed | Vomiting + malaise + hepato-cellular failure | Hospitalization | Labelled | Possible |
| Ketoprofen | Mixed | No | Non serious | Unlabelled | Possible |
| Sulphasalazine | Hepato- | Nausea + vomiting + diarrhoea + abdominal pains | Hospitalization | Unlabelled | Possible |
| Sulphasalazine | Mixed | No | Non serious | Unlabelled | Possible |
| Alimemazine + levomepromazine + Trimipramine | Cholestatic | No | Non serious | Unlabelled only for alimemazine | Possible |
| Fluoxetine + clorazepate | Mixed | No | Non serious | Labelled | Possible |
| Diethylstilbestrol + cyproterone acetate | Cholestatic | No | Non serious | Labelled | Unlikely |
| Isoniazide + Pyrazinamide + rifampicin | Cholestatic | No | Non serious | Labelled | Unlikely |
| Quinapril | Cholestatic | Jaundice | Hospitalisation | Unlabelled | Unlikely |