Table 1.
Population pharmacokinetic parameters and statistical results, two-compartment model, following the administration of 131I-mAbF19 to cancer patients.
Parameter | Population mean value | Standard error of estimate | Intersubject variability (CV) | Standard error of variability estimate |
---|---|---|---|---|
CL (ml h−1) | 109 | 14.6% | 54% | 31% |
Q (ml h−1) | 142 | 18.2% | a | a |
V (l) | 3.13 | 10.8% | 37% | 49% |
Vss (l) | 4.87 | 9.2% | 31% | 45% |
Residual variability | 12.5% | 31% |
not in final model.