Table 2.
Use of ASA and Other Salicylates Among 373 Cases of SCAR and 1720 Controls According to Type of Preparation and Disease Classification.
| Class | Drug | Type of preparation | Cases | Controls | Crude relative risk estimate | Multivariate relative risk estimate (95% confidence interval) |
|---|---|---|---|---|---|---|
| SJS | ASA | Single ingredient | 12 | 92 | 1.6 | 1.2 (0.5,2.6) |
| Combination | 2 | 12 | – | – | ||
| Other salicylates | Single ingredient | 3 | 26 | 1.4 | 1.4 (0.3,4.6)* | |
| Combination | 1 | 3 | – | – | ||
| Overlap | ASA | Single ingredient | 7 | 92 | 1.3 | 1.7 (0.6,4.6) |
| SJS/TEN | Combination | 4 | 12 | 5.7 | 3.6 (0.6,21) | |
| Other salicylates | Single ingredient | 3 | 26 | 2.0 | 2.0 (0.4,6.6)* | |
| Combination | 1 | 3 | – | – | ||
| TEN | ASA | Single ingredient | 12 | 92 | 2.1 | 1.5 (0.6,3.9) |
| Combination | 0 | 12 | – | – | ||
| Other salicylates | Single ingredient | 2 | 26 | – | – | |
| Combination | 0 | 3 | – | – |
Crude estimate.