Table 2.

Range of target minimum effective concentrations (MEC) based on protein binding corrected IC₉₅ values for individual PIs.

Protease inhibitors	MEC
(PIs)	nm	ng ml−1
Amprenavir	588–785	300*–400
Indinavir	97–160	60–100*
Nelfinavir	700–1228	400*–700
Ritonavir	2080–2910	1500–2100*
Saquinavir	150–300	100*–200

Note: different laboratories have used slightly different cut off values.

^*Indicates values used in the Liverpool HIV Pharmacology Group.