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. 2001 May;51(5):461–470. doi: 10.1046/j.1365-2125.2001.01386.x

Table 1.

Inactivation parameters for verapamil and diltiazem.

	Verapamil			Diltiazem
	k_inact (min⁻¹)	K_I (µm)	r	k_inact (min⁻¹)	K_I (µm)	r
HL7	0.16	2.9	7.6	0.07	2.2	18.1
HL12	0.18	2.3	12.2	0.08	2.8	20.8
HL16	0.10	3.4	11.1	0.06	5.0	20.1
Mean ± s.d.	0.15 ± 0.04	2.9 ± 0.6	10.3 ± 2.0	0.07 ± 0.01	3.3 ± 1.5	19.7 ± 1.1

k_inact – maximum inactivation rate constant. K_I – dissociation constant for the enzyme-inactivator complex. r – partition ratio.