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Plasma concentration-time profile for dihydroartemisinin following 312 µmol i.v. artesunate (•), 391 µmol oral artesunate (○) or 422 µmol oral dihydroartemisinin (▵) in group 1 volunteers (a), group 2 volunteers (b) and group 3 patients (c). Data shown as mean±s.d.).
