Table 1.
Venous diameter (mm, mean ± s.e. mean) recorded following the administration of systemic treatments and during the infusion of saline (‘baseline’), phenylephrine hydrochloride solution (‘preconstriction’), and phenylephrine hydrochloride + six different doses of isoprenaline hydrochloride (1–6). See text for details.
Phenylephrine+isoprenaline | ||||||||
---|---|---|---|---|---|---|---|---|
Saline | Phenylephrine | 1 | 2 | 3 | 4 | 5 | 6 | |
Placebo | 0.73 ± 0.11 | 0.19 ± 0.05 | 0.22 ± 0.05 | 0.26 ± 0.05 | 0.34 ± 0.06 | 0.44 ± 0.07 | 0.52 ± 0.08 | 0.59 ± 0.09 |
Bisoprolol 5 mg | 0.76 ± 0.07 | 0.24 ± 0.05 | 0.28 ± 0.06 | 0.32 ± 0.05 | 0.36 ± 0.05 | 0.43 ± 0.07 | 0.52 ± 0.07 | 0.62 ± 0.07 |
Nadolol 40 mg | 0.78 ± 0.11 | 0.14 ± 0.03 | 0.14 ± 0.03 | 0.17 ± 0.04 | 0.23 ± 0.04 | 0.31 ± 0.07 | 0.38 ± 0.07 | 0.47 ± 0.09 |