Table 5.
Effect of systemic drug treatments in the absence and presence of isoprenaline on the cardiovascular measures: heart rate (HR: beats min−1), systolic blood pressure (SBP: mmHg), and diastolic blood pressure (DBP: mmHg), difference (mean, 95% CI, n = 12) between placebo (Pl) and bisoprolol 5 mg (BIS5), placebo and nadolol 40 mg (NAD40), and bisoprolol 5 mg and nadolol 40 mg.
| HR (beats min−1) | SBP (mmHg) | DBP (mmHg) | |
|---|---|---|---|
| In the absence of isoprenaline | |||
| Pl vs BIS5 | −10.3 (−16.4, −4.2) | −14.6 (−23.4, −5.8) | −5.3 (−8.8, −1.7) |
| Pl vs NAD40 | −7.5 (−11.5, −3.5) | −9.58 (−16.42, −2.75) | −4.0 (−9.0, 1.0) |
| BIS5 vs NAD40 | 2.8 (−4.0, 9.6) | 5.0 (−1.1, 11.1) | 1.3 (−2.7, 5.2) |
| In the presence of isoprenaline | |||
| Pl vs BIS5 | −9.5 (−13.73, −5.27) | −13.2 (−21.2, −5.1) | 5.8 (1.1, 10.4) |
| Pl vs NAD40 | −13.3 (−18.5, −8.0) | −14.0 (−21.8, −6.2) | 7.9 (2.3, 13.6) |
| BIS5 vs NAD40 | −3.8 (−8.1, 0.6) | −0.8 (−6.9, 5.2) | 2.2 (−0.1, 4.4) |