Table 6.
Predictive performance of carbamazepine population pharmacokinetic models in a group of patients (n = 30). (95% confidence interval).
| Regression | Bayesian | |
|---|---|---|
| Basic model | ||
| MPE (mg l−1) | −0.57 | −0.66 |
| (−1.57–0.43) | (−1.55–0.23) | |
| RMSE (mg l−1) | 3.59 | 3.2 |
| (2.41–4.47) | (2.03–4.04) | |
| Population covariate model | ||
| MPE (mg l−1) | −0.31 | 0.23 |
| (−1.33–0.71) | (−0.28–0.74) | |
| RMSE (mg l−1) | 2.69 | 1.65 |
| (1.51–3.49) | (1.33–1.91) | |
MPE = mean prediction error; RMSE = root mean squared error.