Table 3.
Summary of prospective studies on ADRs leading to hospitalization in children.
| Setting/year [ref.] | Population studied | ADRs occurrence |
|---|---|---|
| Paediatric teaching hospital | 3556 paediatric admissions | 72 admissions for ADRs (2%): |
| Gainesville (USA) | Age not reported | 69 (96%) definite/probable |
| 1976 (26 | 28 (39%) severe | |
| Teaching hospital | 906 paediatric admissions | 29 admissions for ADRs (3.2%): |
| Jerusalem (Israel) 1982 [27] | Age range: 0–16 years | 19 (66%) definite/probable12 (45%) severe |
| Teaching and community hospitals | 6546 paediatric admissions | 131 admissions for ADRs (2%): |
| Boston (USA) | Age range: 0–15 years | 67 (51%) definite/probable |
| 1988 [28] | Severity not reported | |
| Paediatric teaching hospital | 512 paediatric admissions | 21 admissions for ADRs (4.1%): |
| Valencia (Spain) | Age range: 4 months-2 years | 16 (76%) definite/probable |
| 1996 [29] | Mean age: 9 months | 8 (38%) severe |
| Paediatric teaching hospital | 1682 paediatric admissions | 10 admissions for ADRs |
| Melbourne (Australia) | Age range: 4 months−18 years | 3 (30%) definite/probable |
| 1998 [30] | Mean age: 9 years | Severity not reported |