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. 2001 Jul;52(1):85–91. doi: 10.1046/j.0306-5251.2001.01406.x

Table 5.

Some examples of modifications of prescription only medicines (POM).

Sildenafil not dispensed because of interaction with isosorbide mononitrate and because of contraindication in angina pectoris.
Erythromycin changed to doxycycline because of interaction with cisapride.
Dexamethasone eye drops not dispensed and changed to hypromellose eye drops because of too prolonged use.
First prescription of itraconazole dispensed for 7 days instead of 3.5 days because of too short use.
Tablets with paracetamol (500 mg) + codeine (20 mg) not dispensed because of double medication with naproxen 500 mg and paracetamol 500 mg, prescribed by other doctor.
Capsules with paracetamol, dexchlorpheniramine and ephedrine changed to capsules with paracetamol and dexchlorpheniramine because of contraindication in hypertension.
Amoxicillin changed to clarithromycin because of hypersensitivity.