Table 1.
Incidence estimates of drug related hospital admissions combined over 5 quarters and their sensitivity to a larger source population defined by 70% of cumulative admissions.
| Source population defined by 60% cumulative admissions (25 postal codes) | Source population defined by 70% cumulative admissions (44 postal codes) | ||||||
|---|---|---|---|---|---|---|---|
| Medication group | Number ADRs | Treated patients | Incidence⋆ | 95% Cl⋆⋆ | Treated patients | Incidence | 95% Cl |
| NSAIDs | 47 | 85030 | 5.53 | 3.94, 7.11 | 146416 | 3.21 | 2.29, 4.13 |
| Antithrombotics | 98 | 40338 | 24.30 | 19.5, 29.1 | 64071 | 15.3 | 12.3, 18.3 |
| Systemic corticosteroids | 19 | 14989 | 12.68 | 6.10, 18.4 | 24624 | 7.72 | 4.25, 11.2 |
| ACE inhibitors | 14 | 60875 | 2.30 | 1.10, 3.50 | 102288 | 1.37 | 0.65, 2.08 |
| Diuretics | 7 | 37901 | 1.85 | 0.47, 3.22 | 66041 | 1.06 | 0.27, 1.85 |
| Digitalis | 15 | 62055 | 2.42 | 1.19, 3.64 | 100153 | 1.50 | 0.74, 2.26 |
| Calcium antagonists | 19 | 84097 | 2.26 | 1.24, 3.28 | 134692 | 1.41 | 0.78, 2.05 |
| β-adrenoceptor blockers | 11 | 55857 | 1.97 | 0.81, 3.13 | 91822 | 1.20 | 0.49, 1.91 |
| Nitrates | 13 | 84612 | 1.54 | 0.70, 2.37 | 144420 | 0.90 | 0.41, 1.39 |
| Insulin | 34 | 29327 | 11.6 | 7.70, 15.5 | 47730 | 7.12 | 4.73, 9.52 |
| Oral antidiabetics | 21 | 41264 | 5.09 | 2.91, 7.27 | 72429 | 2.90 | 1.66, 4.14 |
Incidence of drug related hospital admissions per 10 000 treated patients.
Cl = confidence interval assuming Poisson distributed errors.