Table 2.
Risk of first-time acute myocardial infarction associated with the use of antidepressants.
| Antidepressant use | Cases (n = 3315) | Controls (n = 13 139) | Adjusted⋆ odds ratio (95% Confidence Interval) |
|---|---|---|---|
| Non-use | 2853 | 11 507 | 1.0 (Referent) |
| SSRI† use | |||
| Current | 13 | 51 | 0.9 (0.5–1.8) |
| Recent past | 2 | 8 | 1.0 (0.2–4.7) |
| Past | 32 | 115 | 1.0 (0.7–1.5) |
| Non-SSRI use | |||
| Current | 85 | 333 | 0.9 (0.7–1.2) |
| Recent past | 8 | 27 | 1.2 (0.6–2.7) |
| Past | 230 | 776 | 1.2 (1.0–1.3) |
| Others | |||
| Current | 8 | 26 | 1.3 (0.6–2.8) |
| Recent past | 0 | 3 | – |
| Past | 5 | 32 | 0.6 (0.2–1.5) |
| Mixed | 79 | 261 | 1.1 (0.9–1.5) |
adjusted for smoking status and body mass index.
SSRI indicates selective serotonin reuptake inhibitor.